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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1981-7-20
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pubmed:abstractText |
Eyes undergoing routine intracapsular cataract extraction (without alpha-chymotrypsin) often experience marked ocular hypertension in the first six hours after surgery. We conducted a randomized, prospective, double-blind study to determine if timolol maleate would prevent this increase in pressure. Thirty-five eyes undergoing routine cataract extraction were given a drop of either timolol 0.5% or placebo twice before and twice after surgery. Nine (56.3%) of 16 control eyes and 2 (10.5%) of 19 timolol-treated eyes had pressures above 30 mm Hg at six hours after surgery (P less than 0.025). Thus, prophylactic timolol 0.5% can substantially reduce the incidence of severe early postoperative ocular hypertension.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0161-6420
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
88
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
233-8
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:7015220-Cataract Extraction,
pubmed-meshheading:7015220-Clinical Trials as Topic,
pubmed-meshheading:7015220-Double-Blind Method,
pubmed-meshheading:7015220-Humans,
pubmed-meshheading:7015220-Intraocular Pressure,
pubmed-meshheading:7015220-Ophthalmic Solutions,
pubmed-meshheading:7015220-Propanolamines,
pubmed-meshheading:7015220-Random Allocation,
pubmed-meshheading:7015220-Timolol
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pubmed:year |
1981
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pubmed:articleTitle |
Prophylactic timolol for the prevention of high intraocular pressure after cataract extraction. A randomized, prospective, double-blind trial.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|