Linked Life Data

7008501

Source:http://linkedlifedata.com/resource/pubmed/id/7008501

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1981-4-13
pubmed:abstractText
Sputum sol phase from seventeen cystic fibrosis (CF) patients chronically infected in the lungs with mucoid Pseudomonas aeruginosa and presenting multiple precipitins in serum against this bacterium (CF + P) and 11 CF patients without P. aeruginosa infection (CF-P) were examined for proteolytic activity in a fibrin plate assay. The proteolytic activity was significantly higher (p smaller than 0.02) in sputum from CF + P patients than in sputum from CF-patients. This difference was only quantitative since sputum sol phase from both groups degraded fibrinogen to non-precipitable material. The proteolytic degradation of IgG, IgA, secretory IgA and albumin in the sputum sol phases was investigated by means of gel filtration and the stability of these proteins during various storage conditions was examined. Degradation of IgG, IgA, secretory IgA and albumin in the sputa was not demonstrable and the proteins were stable for at least 4 weeks at 4 degree C.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0304-1328
pubmed:author
pubmed:issnType
Print
pubmed:volume
88
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
275-80
pubmed:dateRevised
2009-6-4
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Immunoglobulins and albumin in sputum from patients with cystic fibrosis. A study of protein stability and presence of proteases.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't