Linked Life Data

7008402

Source:http://linkedlifedata.com/resource/pubmed/id/7008402

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
17
pubmed:dateCreated
1981-4-21
pubmed:abstractText
By means of the Warburg assay (manometric technique), investigations were performed to elucidate interactions between amphotericin B, a polyene antifungal antibiotic, and hydroxytetracycline. Those two compounds were combined in clinical therapy. On resting yeasts and bacteria, interactions could be ruled out. On the contrary, on both types of microbes a significant increase in antimicrobial actions could be seen in the presence of the second substance. The antimycetic activity of amphotericin B was significantly increased in the presence of hydroxytetracycline (in five-fold concentrations). The antibacterial activity of hydroxytetracycline was significantly higher in the presence of amphotericin B (same concentrations). The clinical implication of these results is briefly discussed.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0301-0481
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1162-71
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
[Interactions between amphotericin B and hydroxytetracycline].
pubmed:publicationType
Journal Article, English Abstract