Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1981-4-24
pubmed:abstractText
Evidence for the existence of dopamine (DA) receptors in structures peripheral to the blood-brain barrier is accumulating. Two important central dopaminergic systems are functionally located peripheral to the blood-brain barrier, viz, the DA receptors in the chemoceptor trigger zone (CTZ) and those in the anterior pituitary. Agonists on these systems induce vomiting and reduce milk production, while antagonists have opposite effects. DA receptors also occur in the proximal gastrointestinal tract where activation of DA receptors delays gastric emptying. DA antagonists, however, enhance gastric emptying and prevent gastro-oesophageal reflux probably via an action on DA receptors in the stomach. DA receptors also occur in renal, mesenteric, coronary and intracerebral arteries. Activation of these DA receptors causes vasodilatation with a resultant increase in regional tissue perfusion.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0256-9574
pubmed:author
pubmed:issnType
Print
pubmed:day
7
pubmed:volume
59
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
329-32
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Peripheral dopaminergic receptors. Physiological and pharmaceutical aspects of therapeutic importance.
pubmed:publicationType
Journal Article, Review