Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1981-3-24
pubmed:abstractText
The distribution and concentration of vasoactive intestinal polypeptide (VIP) in different parts of the female genital organs from various species (cat, goat, pig, rabbit, rat, and guinea pig) were studied by means of immunohistochemistry and immunochemistry. In addition, the effect of VIP on the mechanical activity of uterine muscle was investigated in vitro. VIP immunoreactive nerve fibers innervating vessels and smooth muscle cells were fairly numerous in the genital organs of the cat and goat and less numerous in the pig, rabbit, rat, and guinea pig. In all species studied, VIP-containing nerves were most numerous in the cervix. The tissue concentration of VIP measured by immunochemistry was in agreement with the immunohistochemical findings. VIP inhibited the mechanical uterine activity in the cat, goat, pig, and rabbit, whereas only minimal effects were obtained in the rat and guinea pig. This difference between the species corresponded to the number of VIP-containing nerves in the uterine muscle. The data support the hypothesis that VIP may play a physiological role in the local nervous control of the uterine mechanical activity.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0002-9513
pubmed:author
pubmed:issnType
Print
pubmed:volume
240
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
E32-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Distribution and motor effect of VIP in female genital tract.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't