Linked Life Data

7003044

Source:http://linkedlifedata.com/resource/pubmed/id/7003044

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5-6
pubmed:dateCreated
1981-2-19
pubmed:abstractText
Several tester strains of Salmonella typhimurium, TA-98, TA-100, TA-1535, and TA-1538; Escherichia coli, W3110 (pol A+) and p3438 (pol A-, repair deficient); and Saccharomyces cerevisiae, D3, D4, and D5 were tested for lethal and mutagenic events when exposed to elevated temperatures or to x-band, pulsed microwave radiation at various power densities. When compared to E. coli pol A+ under growing conditions, E. coli pol A- exhibited decreased cell growth when exposed to microwave radiation at power levels at or above 20 mW/cm2 as well as to temperature levels above 42 degrees C. All yeast and other bacterial strains showed cellular lethality at similar microwave intensities and elevated temperatures. When exposed to elevated temperatures in saline, both quiescent yeast and Salmonella strains exhibited lethal events. However, the Salmonella strains tested showed comparatively less induction of genetic events in the quiescent state compared to induction when the cell were actively growing in broth. These results demonstrate that elevated temperatures generated by microwave exposure could produce genetic events in microbial assay systems. If such systems are to be of value in examining the nonthermal genetic potential of microwave radiation, careful control over exposure conditions will be required to eliminate heat-induced genetic events.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0146-4779
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
195-206
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:articleTitle
Cellular effects in microbial tester strains caused by exposure to microwaves or elevated temperatures.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.