rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
7
|
pubmed:dateCreated |
1980-10-21
|
pubmed:abstractText |
Chronic mycoplasms-induced arthritis of rabbits was accompanied by a highly active humoral immune response. Peak antibody titers coincided with the "disappearance" of mycoplasmas from joint tissues at 7 weeks. High synovial fluid antibody titers and immunoglobulin-producing cells in frozen sections of synovial membrane suggested local antibody production. Persistence of granular deposits containing IgG and complement in synovium and cartilage may be a mechanism for continuing inflammation in the apparent absence of cultivable mycoplasmas.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0004-3591
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
23
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
837-45
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:6996689-Animals,
pubmed-meshheading:6996689-Antibody Formation,
pubmed-meshheading:6996689-Antibody-Producing Cells,
pubmed-meshheading:6996689-Antigen-Antibody Complex,
pubmed-meshheading:6996689-Arthritis,
pubmed-meshheading:6996689-Cartilage, Articular,
pubmed-meshheading:6996689-Chronic Disease,
pubmed-meshheading:6996689-Complement Fixation Tests,
pubmed-meshheading:6996689-Complement System Proteins,
pubmed-meshheading:6996689-Female,
pubmed-meshheading:6996689-Fluorescent Antibody Technique,
pubmed-meshheading:6996689-Mycoplasma,
pubmed-meshheading:6996689-Rabbits,
pubmed-meshheading:6996689-Synovial Membrane
|
pubmed:year |
1980
|
pubmed:articleTitle |
Chronic arthritis of rabbits induced by mycoplasmas. II. Antibody response and the deposition of immune complexes.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|