Linked Life Data

6992971

Source:http://linkedlifedata.com/resource/pubmed/id/6992971

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1980-9-23
pubmed:abstractText
Periodic acid-Schiff-positive diastase-resistant globules are described in an undifferentiated (embryonal) sarcoma of the liver in a 14-year-old boy. These globules were shown to contain alpha-1-antitrypsin (A-1-AT) protein by immunofluorescence techniques. Further immunohistochemical studied revealed albumin and gamma globulins, but no alpha-feto protein (AFP). Electron microscopic studies showed large, electron-dense bodies consistent with phagolysosomal structures, and distinct from that described in alpha-1-antitrypsin deficiency (A-1-ATD). These findings suggested that the globules in this tumor may represent trapping of serum proteins by the malignant cell. These observations are discussed in connection with recent studies linking the deficiency disease and epithelial hepatic tumors.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0008-543X
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
45
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3108-13
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Undifferentiated (embryonal) sarcoma of the liver with alpha-1-antitrypsin deposits: immunohistochemical and ultrastructural studies.
pubmed:publicationType
Journal Article, Case Reports