Linked Life Data

6991127

Source:http://linkedlifedata.com/resource/pubmed/id/6991127

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1980-8-15
pubmed:abstractText
One of the earliest events observed in the 'dedifferentiation phase' of traumatic regeneration is an in vivo increase in transcription. In order to see whether that increase corresponds to a variation at the level of genetic material, we prepared chromatin from normal and regenerating animals (12 h after amputation) for transcription in vitro by E. coli RNA polymerase. The template activity of regenerating chromatin was 2.1-fold higher than normal under standard conditions and showed an altered response to variation of the ionic strength of the medium. The accessibility of DNA in the chromatin was tested using mild digestion by DNAase II. Almost twice as much DNA was solubilised from regenerating chromatin as from normal chromatin. These data were correlated with morphological changes (decondensation) observed by electron microscopy.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0045-6039
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
83-93
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Variations in accessibility of DNA during traumatic regeneration by Owenia fusiformis (polychaete annelid).
pubmed:publicationType
Journal Article