Linked Life Data

6988726

Source:http://linkedlifedata.com/resource/pubmed/id/6988726

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5757
pubmed:dateCreated
1980-6-16
pubmed:abstractText
Autoregulation of mammalian renal function is implicit in the fact that a few hours after removal of one kidney the activity of the intact nephrons in the other kidney suddenly increases, both in glomerular filtration and tubular reabsorption. There follows a slower but easily measured increase in renal mass-compensatory hypertrophy in each residual nephron. That response to a reduction of nephrons has been well studied, but the adaptation of normal renal function to additional nephrons could not be tested until microsurgical techniques made it possible to transplant one or two additional kidneys into normal rats. We report here sequential measurements of the total renal function of rats with three and four kidneys. Our results indicate that autoregulation maintains total renal function at normal levels in spite of a doubling in the number of nephrons and apparent renal mass.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0028-0836
pubmed:author
pubmed:issnType
Print
pubmed:day
17
pubmed:volume
284
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
618-20
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Autoregulation in rats with transplanted supernumerary kidneys.
pubmed:publicationType
Journal Article