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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1980-4-25
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pubmed:abstractText |
Patients with a healed duodenal ulcer and who were symptom-free following 12 months of maintenance treatment with cimetidine 400 mg twice daily were randomized double-blind to a further 6 months therapy with either cimetidine 400 mg twice daily or placebo 2 tablets twice daily. Twenty-six patients received placebo and 15 patients cimetidine. Relapse was defined as symptoms for 3 out of 7 consecutive days and ulcer recurrence was confirmed by independent endoscopy. One of 15 patients on cimetidine relapsed: 20 of 26 patients on placebo relapsed. This relapse rate (77%) is similar to that found in previous studies after only 6 weeks cimetidine therapy (71%). This study suggests that 12 months cimetidine does not change the tendency of duodenal ulcer to recur and that the relapse rate is no greater than after 6 weeks cimetidine.
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0163-2116
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
25
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
88-91
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:6986242-Adolescent,
pubmed-meshheading:6986242-Adult,
pubmed-meshheading:6986242-Aged,
pubmed-meshheading:6986242-Cimetidine,
pubmed-meshheading:6986242-Clinical Trials as Topic,
pubmed-meshheading:6986242-Double-Blind Method,
pubmed-meshheading:6986242-Duodenal Ulcer,
pubmed-meshheading:6986242-Female,
pubmed-meshheading:6986242-Follow-Up Studies,
pubmed-meshheading:6986242-Guanidines,
pubmed-meshheading:6986242-Humans,
pubmed-meshheading:6986242-Male,
pubmed-meshheading:6986242-Middle Aged,
pubmed-meshheading:6986242-Placebos,
pubmed-meshheading:6986242-Recurrence
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pubmed:year |
1980
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pubmed:articleTitle |
Relapse rate of duodenal ulcer after cessation of long-term cimetidine treatment: a double-blind controlled study.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|