Linked Life Data

6985365

Source:http://linkedlifedata.com/resource/pubmed/id/6985365

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1984-9-14
pubmed:abstractText
In order to study gastrointestinal irritation caused by the intake of Benoxaprofen, blood loss in stools before and after intake of the drug was measured by labelling red blood cells with 51Cr. The results were compared with previous studies in which the same method was used to determine fecal blood loss after intake of other non-steroidal anti-inflammatory drugs. Anti-inflammatory drugs inhibiting prostaglandin synthetase caused abnormal fecal blood loss in 20 to 60% of the patients. Benoxaprofen which is a weak prostaglandin synthetase inhibitor and acts on the leukotrienes, entailed no abnormal fecal blood loss. It was concluded that with respect to microbleeding, Benoxaprofen had no harmful effect on the gastrointestinal tract in this population.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0770-3198
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
263-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Gastrointestinal blood loss after intake of benoxaprofen.
pubmed:publicationType
Journal Article, Comparative Study