Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1983-1-7
pubmed:abstractText
Three subpopulations of surface immunoglobulin positive B cells were defined using monoclonal antibodies directed against IgM and IgD antigenic determinants and 2-color fluorescence activated cell sorter analysis: cells with a high density of sIgM and lacking sIgD (M++D-); cells with slightly less sIgM and dully positive for sIgD (M++D+), and cells with a low density of sIgM but brightly staining with anti-IgD (M+D+). In the spleen of two-week-old animals the M++D- cells are the more numerous. Their frequency declines during development in favor of the adult M+D+ cells. Because the densities of sIgM and sIgD on M+D+ cells are positively correlated it is hypothesized that immature M++D- cells first lose their sIgM and then reaquire sIgM together with sIgD.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0065-2598
pubmed:author
pubmed:issnType
Print
pubmed:volume
149
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
103-9
pubmed:dateRevised
2005-11-17
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Fluorescence activated cell sorter analysis of murine B cell development.
pubmed:publicationType
Journal Article