Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1982-7-22
pubmed:abstractText
Isoproterenol (IPR) induces myocardial lesions in R. pipiens adapted to +25 degrees C, but not to +8 degrees C. The spontaneous healing of these lesions in the form of ventricular wall aneurysms occurs during the first three weeks after IPR, and the ultrastructure of the myocardial cells in fully restored from the fourth week after IPR. Leukocytes, adhering to the lacunar endothelium and including phagocytic vacuoles, appear 8-15 days after IPR. Severely altered heart muscle cells then contain myelin figures or a pyknotic nucleus. In the acute stage of the IPR-lesions, heart muscle preparations from the ventricular wall show a very lowered resistance towards cyanide anoxia as judged from the isometric force decay. During the seven weeks of observation after IPR the resistance to cyanide anoxia is continuously improved almost to normal values. Thus restoration of structure and function occurs in parallel.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0108-0164
pubmed:author
pubmed:issnType
Print
pubmed:volume
90
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
57-65
pubmed:dateRevised
2009-6-4
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
The healing of frog heart lesions induced by isoproterenol injections.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't