Linked Life Data

6978559

Source:http://linkedlifedata.com/resource/pubmed/id/6978559

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1982-6-21
pubmed:abstractText
Skin graft rejection was previously shown to be mediated by sensitized lymphocytes bearing the Thy-1+, Ly-1+2-3- cell surface phenotype and these cells were further characterized using antisera to the Ly-5, 6, and 7 specificities. By using an adoptive transfer system in which ATXBM mice (CBA/H) received sensitized cells treated with antiserum and complement, it was shown that the cells mediating skin graft rejection were of the Ly-5+6-7+ phenotype. Other studies have demonstrated that cytotoxic T cells are Ly-5+6+7-, whereas helper T cells are Ly-5+6-7+, so that the T cells-mediating graft rejection is again clearly distinguished from the cytotoxic T. cell. At this time, however, it is not possible to separate the T cells mediating helper T cell functions, delayed-type hypersensitivity (DTH), and allograft rejections.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0041-1337
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
411-3
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Cells mediating graft rejection in the mouse. IV. The Ly-5, 6, and 8 effector cell phenotype.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't