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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1982-6-21
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pubmed:abstractText |
The exposure of Chinese hamster V79 cells to 0.05 or 1.5 M NaCl immediately after combined treatment with heat and X-rays resulted in fixation of potentially lethal damage. The synergistic damage resulting from the interaction of heat and X-rays responded to anisotonic treatment like X-ray damage when heating was at 44.0 or 45.0 degrees C and like heat damage when heating was at 41.5 or 42.0 degrees C. When anisotonic treatment was given before heat plus X-ray exposure, sensitization occurred but the differences between heating at 42.0 and 45.0 degrees C were not as large. Incubation at 37 degrees C between heat and X-ray treatments or between X-ray and heat treatments resulted in recovery as manifested by a decrease in the fixation of damage by subsequent anisotonic treatment. Recovery was also observed when cells were incubated at 37 degrees C between the combined exposure to heat plus X-rays and the anisotonic treatment. These data imply that the lesions produced by heat plus X-ray treatments, which are susceptible to salt fixation, can be repaired.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0020-7616
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
633-43
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:6978300-Animals,
pubmed-meshheading:6978300-Cell Survival,
pubmed-meshheading:6978300-Cricetinae,
pubmed-meshheading:6978300-Cricetulus,
pubmed-meshheading:6978300-Hot Temperature,
pubmed-meshheading:6978300-Hypotonic Solutions,
pubmed-meshheading:6978300-Saline Solution, Hypertonic,
pubmed-meshheading:6978300-Sodium Chloride
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pubmed:year |
1981
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pubmed:articleTitle |
The effect of hypo- and hypertonic NaCl solutions on cellular damage resulting from combined treatments of heat and X-rays.
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pubmed:publicationType |
Journal Article
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