Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1982-5-27
pubmed:abstractText
The surge in current thinking and research on aging, replete with causes and/or effects, has greatly stimulated serious biologists concerned with giving counsel for the feeding and management of animals to reevaluate present practices. This is particularly true for the feeding of dogs. If we are indeed concerned with the feeding of the geriatric dog, we must begin to emphasize changes in nutritional practices that go back to the period preceding birth. Unrestricted caloric intake of dogs during periods of growth and development, even when in proper balance with intake of essential nutrients, has been shown to accelerate somatic processes, resulting in delayed maturation of cartilage and excessive bone apposition. This was followed by reduced bone resorption and remodeling. These processes were associated with the development of either earlier or more severe degenerative diseases of the skeletal system. Studies with rodents have demonstrated damaging effects of unrestricted dietary intake on longevity itself. Most damaging have been the decreasing efficiency of cellular immunity and corresponding increases in autoimmune responses during later life. Judicious caloric restriction beginning even in adult life can have a rejuvenating effect on immune response capacity. Regardless of age, a controlled nutrient intake seems the order of the day. Returning to Lucretius, the graves are indeed being dug with teeth.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0195-5616
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
669-75
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Nutrition and the aging animal.
pubmed:publicationType
Journal Article