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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1981-12-15
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pubmed:abstractText |
Cytogenetic studies were performed on leukemic cells from two patients with adult T-cell leukemia. A 14q+ marker chromosome was found in the peripheral blood leukocytes from patient No. 1 and in a leukemic T-cell line (MT-1) derived from the peripheral blood of patient No. 2. The 14q+ resulted from a t(12;14) in patient No. 1 and from a t(Y;14) in patient No. 2 with a break point at 14q32 in each case. In addition, the leukemic cells from patient No. 1 showed a t(1;7) and a 9q-, while the MT-1 line had numerous structural abnormalities. Thus, it is clear that a 14q+ translocation is not restricted to B-cell neoplasms but occurs in T-cell neoplasms as well.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0165-4608
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
251-9
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:6974589-Adult,
pubmed-meshheading:6974589-Aged,
pubmed-meshheading:6974589-Chromosomes, Human, 13-15,
pubmed-meshheading:6974589-Genetic Markers,
pubmed-meshheading:6974589-Humans,
pubmed-meshheading:6974589-Karyotyping,
pubmed-meshheading:6974589-Lymphoma,
pubmed-meshheading:6974589-Male,
pubmed-meshheading:6974589-T-Lymphocytes,
pubmed-meshheading:6974589-Translocation, Genetic,
pubmed-meshheading:6974589-Y Chromosome
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pubmed:year |
1981
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pubmed:articleTitle |
Chromosome 14q+ in adult T-cell leukemia.
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pubmed:publicationType |
Journal Article,
Case Reports
|