Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1981-9-25
pubmed:abstractText
A major disadvantage in studying the effects of chemicals on the radiation response of mammalian cells in vitro can be the poor water solubility of the chemicals. Using Chinese hamster cells we have overcome this problem by using dimethyl sulphoxide and ethanol as co-solvents. From studies using these co-solvents and misonidazole as a standard we have demonstrated that these co-solvents have no effect on sensitizing efficiency and cytotoxicity. A number of poorly water soluble 2-nitroimidazoles of promising structure have been studied. The results, together with those from studies on misonidazole and the co-solvents are presented.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0020-7616
pubmed:author
pubmed:issnType
Print
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
633-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Use of solubilizing agents to study radiosensitization in vitro by compounds of low water solubility.
pubmed:publicationType
Journal Article, In Vitro