Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1981-8-10
pubmed:abstractText
Two classes of T lymphocytes can mediate delayed-type hypersensitivity (DTH) to influenza virus in the mouse. If non-infectious virus preparations are used to sensitize for or to elicit a DTH response, the effector cells are found to be Ly-1-positive and are I-region-restricted. If infectious virus is used both to sensitize for and to elicit the reaction, a second set of effector cells is also directed, which are Ly-2,3-positive and are D- or K,D-region-restricted. The latter cells are cross-reactive within the A strains of influenza viruses, and pretreatment of the mice with high doses of cyclophosphamide markedly decreases their generation in the spleens of sensitized mice, suggesting that the cells that demonstrate DTH activity in vivo may also have cytotoxic activity in vitro.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0300-9475
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
481-7
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Two T-cell populations mediate delayed-type hypersensitivity to murine influenza virus infection.
pubmed:publicationType
Journal Article