rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1981-2-19
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pubmed:abstractText |
The antigenic properties of leukaemic cells from five patients with adult T cell leukaemia were studied with rabbit anti-MOLT-4 and anti-human thymocyte antisera using indirect membrane immunofluorescent staining. The E rosette-positive, surface immunoglobulin (sIg) negative leukaemic cells from these patients gave a positive reaction with the appropriately absorbed antisera, which reacted specifically with thymocytes, cells from T cell acute lymphoblastic leukaemia (T-ALL) and T-ALL-derived lymphoblastoid cell lines (T-LCLs) and normal peripheral blood T cells. Nevertheless, the antisera further absorbed with fresh normal peripheral blood lymphocytes (FN-PBL) lost almost all the reactivities with the leukaemic cells as well as with normal peripheral blood T cells but still retained the reactivities with thymocytes, T-LCLs and T-ALL cells. The results suggest that adult T cell leukaemia cells possess a peripheral blood T cell antigen but not a thymocyte-specific antigen.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/6969147-1089710,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6969147-1100719,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6969147-159121,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6969147-197412,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6969147-301762,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6969147-302342,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6969147-302734,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6969147-315787,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6969147-342007,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6969147-356954,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6969147-4567231,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6969147-53372
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0009-9104
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
130-5
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:6969147-Adult,
pubmed-meshheading:6969147-Aged,
pubmed-meshheading:6969147-Antigens, Neoplasm,
pubmed-meshheading:6969147-Humans,
pubmed-meshheading:6969147-Leukemia, Lymphoid,
pubmed-meshheading:6969147-Male,
pubmed-meshheading:6969147-Middle Aged,
pubmed-meshheading:6969147-Receptors, Antigen, B-Cell,
pubmed-meshheading:6969147-Rosette Formation,
pubmed-meshheading:6969147-T-Lymphocytes
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pubmed:year |
1980
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pubmed:articleTitle |
Immunological distinction of adult T cell leukaemia from T cell acute lymphoblastic leukaemia.
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pubmed:publicationType |
Journal Article,
Case Reports
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