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Predicate | Object |
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rdf:type | |
lifeskim:mentions |
umls-concept:C0017710,
umls-concept:C0021345,
umls-concept:C0024264,
umls-concept:C0036667,
umls-concept:C0039194,
umls-concept:C0185023,
umls-concept:C0205296,
umls-concept:C0205360,
umls-concept:C0237497,
umls-concept:C0237876,
umls-concept:C0312418,
umls-concept:C1314972,
umls-concept:C1368474,
umls-concept:C1521970,
umls-concept:C1879547,
umls-concept:C1947904,
umls-concept:C1999228,
umls-concept:C2825781
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pubmed:issue |
3
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pubmed:dateCreated |
1980-12-16
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pubmed:abstractText |
Blood lymphocytes of infectious mononucleosis (IM) patients, unlike these obtained from healthy individuals, exhibit the following characteristics of activated T cells: (1) "stable" E rosette formation; (2) natural attachment to various human normal and malignant cells; (3) sensitivity in vitro to the lytic effect of glucocorticoids. Although the IM T cells attach in vitro to all the human cells tested, they kill only the EBV genome carrying targets. The possibility is discussed that some of the activated T cells in IM result from a non-specific activation elicited by the T cells responding specifically to the EBV associated antigens.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0141-2760
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
153-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6968353-Cell Adhesion,
pubmed-meshheading:6968353-Cytotoxicity, Immunologic,
pubmed-meshheading:6968353-Humans,
pubmed-meshheading:6968353-Hydrocortisone,
pubmed-meshheading:6968353-Infectious Mononucleosis,
pubmed-meshheading:6968353-Rosette Formation,
pubmed-meshheading:6968353-T-Lymphocytes
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pubmed:year |
1980
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pubmed:articleTitle |
Blood lymphocytes in infectious mononucleosis share the following characteristics with activated T cells: natural attachment, stable E rosetting and glucocorticoid sensitivity.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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