Linked Life Data

6965577

Source:http://linkedlifedata.com/resource/pubmed/id/6965577

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1980-4-23
pubmed:abstractText
Eight patients with mycosis fungoides (seven in plaque stage and one with tumors) were successfully treated with methoxalen-ultraviolet-A (PUVA) photochemotherapy. A selective immunity evaluation had been carried out prior to starting treatment and was repeated sevedn to 33 months (mean, 22 months) later. The results of pre-PUVA and post-PUVA therapy evaluation were compared. The delayed hypersensitivity responses improved in all eight patients, and four patients who were anergic before treatment manifested a normal response after PUVA therapy. The T lymphocyte counts were reduced in four patients before PUVA therapy (mean +/- SD, 66.72% +/- 9.78%) and in seven patients after PUVA (mean +/- SD, 54.43% +/- 10.86%; P = .03). The results of mitogen stimulation studies with phytohemagglutinin, pokeweed mitogen, and concanavalin A were equivocal. The levels of serum immunoglobulins were not affected. One patient had a positive antinuclear factor test of low titer.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0003-987X
pubmed:author
pubmed:issnType
Print
pubmed:volume
116
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
178-81
pubmed:dateRevised
2008-3-17
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Immunologic evaluation in mycosis fungoides. Before and after PUVA therapy.
pubmed:publicationType
Journal Article, Comparative Study