Linked Life Data

6962540

Source:http://linkedlifedata.com/resource/pubmed/id/6962540

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1983-4-7
pubmed:abstractText
The mode of action of colloidal bismuth subcitrate (CBS), a colloidal bismuth preparation often used in the treatment of gastroduodenal ulcers, is unknown. The precipitation characteristics of CBS were determined by titration with hydrochloric acid and gastric juice. The precipitation pH were 4.0 and 3.5 respectively. Preoperative administration of CBS resulted in a preferential accumulation of bismuth in chronic gastric ulcers as determined by tissue bismuth assays. CBS and gastric glycoprotein formed an in vitro complex which markedly retarded the migration of H+. One of the mechanisms by which CBS promotes ulcer healing is through its behaviour as a diffusion barrier to hydrochloric acid.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0085-5928
pubmed:author
pubmed:issnType
Print
pubmed:volume
80
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
17-21
pubmed:dateRevised
2008-2-13
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
A potential mechanism of action of colloidal bismuth subcitrate: diffusion barrier to hydrochloric acid.
pubmed:publicationType
Journal Article