Linked Life Data

6958350

Source:http://linkedlifedata.com/resource/pubmed/id/6958350

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1983-1-19
pubmed:abstractText
The cellular DNA content was determined in a consecutive series of 26 classical and two paraosteal osteosarcomas by means of single cell cytophotometry. All classical osteosarcomas regardless of histologic type (osteo-, chondro-, fibroblastic) or grade were found to be hyperploid (abnormally increased DNA content) while both paraosteal osteosarcomas proved to be diploid (normal DNA content). Closer analysis of the DNA distribution curves showed that the majority of the classical osteosarcomas exhibited a triploid modal DNA value and more than 90% hyperploid cells. Cytochemical characterization of osteosarcomas may be of prognostic significance in reflecting the degree of malignancy. The results of the present study indicate that cytophotometric DNA analysis, as an adjunct to conventional histologic evaluation, offers an objective means of differentiating between classical and paraosteal osteosarcomas.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0008-543X
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2476-81
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Cellular DNA content in human osteosarcoma: aspects on diagnosis and prognosis.
pubmed:publicationType
Journal Article