Linked Life Data

6957312

Source:http://linkedlifedata.com/resource/pubmed/id/6957312

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1982-12-21
pubmed:abstractText
Quantitative measurement of nonspecific bronchial responsiveness can be simply and reproducibly made by inhalation tests with histamine or methacholine. Responsiveness to histamine correlates closely with responsiveness to methacholine. The degree of responsiveness relates closely with the presence and severity of asthma. The greater the increase in responsiveness the lower the peak flow rate (PFR) on waking, the greater the improvement in PRF after bronchodilator, the greater the diurnal variation of PFR, the easier is bronchoconstriction induced by nonspecific and allergic stimuli and the more treatment is required to control symptoms. Nonspecific responsiveness can be increased by exposure to respirable allergens or occupational sensitizers, and by infection. The observations suggest that measurement can be used in clinical practice to diagnose the presence of asthma, to help assess the severity of asthma and, in the assessment of occupational asthma, to determine if exposure can heighten bronchial responsiveness.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0106-4347
pubmed:author
pubmed:issnType
Print
pubmed:volume
121
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
79-88
pubmed:dateRevised
2008-2-21
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Bronchial responsiveness to histamine or methacholine in asthma: measurement and clinical significance.
pubmed:publicationType
Journal Article