Linked Life Data

6957175

Source:http://linkedlifedata.com/resource/pubmed/id/6957175

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1982-12-2
pubmed:abstractText
We present evidence that cells in fibrous joints respond to tensile mechanical stress by synthesizing significant quantities of type III collagen. Under normal conditions sutural fibroblasts synthesize type I collagen. Type III comprised some 20 per cent of the newly synthesized collagen in stressed joints, a level that was achieved within 24 h of the onset of tension and remained unchanged throughout a 4-day experimental period. These findings suggest that the biomechanical environment of a connective tissue cell is an important determinant of the type of collagen synthesized. However, we propose that the effect is likely to be an indirect one by virtue of its influence on the metabolic activity of the cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0003-9969
pubmed:author
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
609-13
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Rabbit cranial suture fibroblasts under tension express a different collagen phenotype.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't