Linked Life Data

6954835

Source:http://linkedlifedata.com/resource/pubmed/id/6954835

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1982-9-24
pubmed:abstractText
The inactivation of prostaglandin E2(PGE2) and 5-hydroxytryptamine (5-HT) was studied in isolated perfused lungs from fetal and neonatal rabbits. PGE2 inactivation was considerable already at the 28th day of fetal life, as only 11% of injected substrate survived passage through the pulmonary circulation. However, the inactivation increased significantly during the last 3 prenatal days (4% survival) and remained at this level when analyzed one week postnatally. In contrast to PGE2-metabolism, 5-HT inactivation was relatively stable during the studied fetal period (47-49% inactivation), but was decreased significantly on the 7th day postnatally when compared to newborn litters. The results indicate that pulmonary prostaglandin and amine metabolism reach maturity at different times during the perinatal period.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-6772
pubmed:author
pubmed:issnType
Print
pubmed:volume
113
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
291-5
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
The inactivation of prostaglandin E2 and 5-hydroxytryptamine in isolated perfused fetal and neonatal rabbit lungs.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't