rdf:type |
|
lifeskim:mentions |
|
pubmed:dateCreated |
1982-4-12
|
pubmed:abstractText |
The Finnish Leukaemia Group has carried out a randomized, multicenter trial to study the effect of levamisole on the remission maintained with 6-mercaptopurine and methotrexate in acute myeloid leukaemia in adults. Levamisole was given on 3 consecutive days every 2 weeks. Twenty-five patients received only chemotherapy, while 26 patients received levamisole as well. The patients receiving levamisole showed significantly better remission duration than those given only chemotherapy (P = 0.033, Mantel's summary chi 2-text). There are four long term survivors in the levamisole group versus none in the chemotherapy group. The remissions have lasted 48-75 months.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0080-0015
|
pubmed:author |
pubmed-author:AhrenbergPP,
pubmed-author:HänninenAA,
pubmed-author:IkkalaEE,
pubmed-author:LahtinenRR,
pubmed-author:LehtinenMM,
pubmed-author:LevantoAA,
pubmed-author:PalvaII,
pubmed-author:RajamäkiAA,
pubmed-author:RosengartCC,
pubmed-author:RuutuTT,
pubmed-author:SarnaSS,
pubmed-author:SelroosOO,
pubmed-author:TimonenTT,
pubmed-author:VilpoJJ,
pubmed-author:VuopioPP,
pubmed-author:WarisEE,
pubmed-author:WasastjernaCC
|
pubmed:issnType |
Print
|
pubmed:volume |
80
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
70-2
|
pubmed:dateRevised |
2008-2-13
|
pubmed:meshHeading |
pubmed-meshheading:6949237-6-Mercaptopurine,
pubmed-meshheading:6949237-Adult,
pubmed-meshheading:6949237-Aged,
pubmed-meshheading:6949237-Drug Administration Schedule,
pubmed-meshheading:6949237-Follow-Up Studies,
pubmed-meshheading:6949237-Humans,
pubmed-meshheading:6949237-Immunotherapy,
pubmed-meshheading:6949237-Leukemia, Myeloid, Acute,
pubmed-meshheading:6949237-Levamisole,
pubmed-meshheading:6949237-Methotrexate,
pubmed-meshheading:6949237-Middle Aged
|
pubmed:year |
1982
|
pubmed:articleTitle |
The Finnish leukaemia group: levamisole in maintenance therapy of acute myeloid leukemia in adults.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|