Linked Life Data

6946388

Source:http://linkedlifedata.com/resource/pubmed/id/6946388

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1982-1-28
pubmed:abstractText
Buffy coat cells were collected by leukapheresis from 14 patients with C.G.L. and one patient with M.M.M. Six of the C.G.L. patients had received busulphan at intervals varying between 401 and 38 d before leukapheresis. Significantly more CFUc's could be collected per leukapheresis in untreated patients and in those patients not treated within 105 d prior to leukapheresis. Survival of CFUc's following freezing was significantly less in the 3 most recently treated patients. These results suggest that in C.G.L. patients recently treated with busulphan, both the number of CFUc's in the peripheral blood and the ability of these cells to survive the freeze thaw process are reduced. However, sufficient CFUc's could theoretically be collected, stored and recovered post-thaw from one leukapheresis to allow complete haematopoietic restoration in all but 2 patients.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0031-3025
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
609-14
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Collection and cryopreservation of peripheral blood progenitor cells in chronic granulocytic leukaemia--a comparison of treated and untreated patients.
pubmed:publicationType
Journal Article, Comparative Study