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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
|
pubmed:dateCreated |
1981-9-22
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pubmed:abstractText |
HLA frequency distributions in Fiji Indians with non-insulin dependent diabetes were compared with those in control subjects with confirmed two-hour plasma glucose levels less than 7.8 mmol/L. Antigen frequencies at HLA-A and HLA-DR loci were similar in patients and controls. At HLA-B, there was a significant increase in Bw61 (Bw40.2) in diabetics, with a relative risk for this antigen of 4.8. Since a similar finding has been reported previously in South African Indians with Insulin-dependent diabetes, it is possible that wer have defined yet another genetically-distinct form of diabetes, especially prevalent in Indians. Alternatively, definition of new HLA alleles such as Bw61, a new subdivision of an established antigen, may reveal HLA associations with non-insulin dependent diabetes in European Caucasians also.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0025-729X
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
2
|
pubmed:volume |
1
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
462-4
|
pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading | |
pubmed:year |
1981
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pubmed:articleTitle |
HLA and non-insulin dependent diabetes in Fiji indians.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|