Linked Life Data

69414

Source:http://linkedlifedata.com/resource/pubmed/id/69414

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1977-8-25
pubmed:abstractText
Anaplasia refers to the apparent retrogression toward an embryonic state that occurs in some human and animal tumors, the consequence, presumably, of a derepression of genes that would normally have been switched off in the course of development. The fetal substances newly formed in tumors are identified immunologically and are therefore referred to as "antigens." Some such antigens, for example, carcinoembryonic antigen and alpha-fetoprotein, and blood-group precursor substances have great promise diagnostically but play no known part in resistance to malignant growth. The reawakened fetal antigens that are of special interest and importance are those that are capable of arousing cell-mediated immunity and thus may contribute to antitumor immunity. Modern research, therefore, rehabilitates an etiologc notion earlier thought to have been discredited.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0003-4819
pubmed:author
pubmed:issnType
Print
pubmed:volume
87
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
100-2
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Anaplasia rediviva.
pubmed:publicationType
Journal Article