Linked Life Data

6939264

Source:http://linkedlifedata.com/resource/pubmed/id/6939264

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1981-6-25
pubmed:abstractText
In order to define the significance of minimal histological and ultrastructural abnormalities in Duchenne carriers, 18 normal healthy volunteers were examined by muscle biopsy. Light microscopy evidenced occasional internal nuclei and less frequent small round and angular fibres. Variability of fibre size, increase in connective tissue, necroses and basophilia found in carriers were not present in controls. Histograms constructed on ATPase stain sections demonstrated variability in distribution of fibre types both in normals and in carriers. Fibre size was more variable in carriers, where a significant decrease of the size of type II B fibres was observed. Electron microscopy evidenced knots in overcontraction, myofibrillary widening, subsarcolemmal accumulation of mitochondria and Z band streaming, which have been reported also in carriers. The results are discussed and compared with the data of the literature.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0065-1435
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
328-30
pubmed:dateRevised
2007-11-9
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
The significance of minimal alterations in muscle biopsy of Duchenne carriers.
pubmed:publicationType
Journal Article