Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
668
|
pubmed:dateCreated |
1981-3-17
|
pubmed:abstractText |
An evaluation of the efficacy of influenza virus subunit vaccine was undertaken during a study of acute respiratory disease in the semi-isolated community of Port Chalmers, New Zealand. In 1973, the administration of a vaccine containing A/England/42/72(H3N2) and B/Roma/1/67 stains was found to produce HI antibody titres greater than or equal to 1:40 to the A and B components in 50 percent of 32 subjects. There was no significant NI antibody response to the A component. During an epidemic of A/Port Chalmers/I/73(H3N2) occurring three to four months after vaccination, vaccinees were not protected from clinical infection. Sixty and ninety-nine subjects received vaccine containing A/Port Chalmers/1/73 and B/Hong Kong/8/73 in 1974 and 1975 respectively. In 1974 all 60 subjects received a second dose of vaccine which was shown to have little effect on the distribution of HI antibody titres. The benefits of annual vaccination in this general practice are unclear.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0028-8446
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
24
|
pubmed:volume |
92
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
230-3
|
pubmed:dateRevised |
2005-11-22
|
pubmed:meshHeading |
pubmed-meshheading:6935541-Adolescent,
pubmed-meshheading:6935541-Adult,
pubmed-meshheading:6935541-Antibodies, Viral,
pubmed-meshheading:6935541-Child,
pubmed-meshheading:6935541-Child, Preschool,
pubmed-meshheading:6935541-Humans,
pubmed-meshheading:6935541-Influenza, Human,
pubmed-meshheading:6935541-Influenza Vaccines,
pubmed-meshheading:6935541-Middle Aged,
pubmed-meshheading:6935541-New Zealand,
pubmed-meshheading:6935541-Vaccination
|
pubmed:year |
1980
|
pubmed:articleTitle |
A study of acute respiratory disease in the community of Port Chalmers. III. Efficacy of influenza virus subunit vaccines in 1973, 1974 and 1975.
|
pubmed:publicationType |
Journal Article
|