rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
11
|
pubmed:dateCreated |
1981-2-24
|
pubmed:abstractText |
The HLA-A, B, C, and DR antigens were typed in 35 black and 35 white Americans with rheumatoid arthritis. The frequency of HLA-DRw4 was increased in both the black and white patient patient groups compared to the race-matched control groups. DRw4 was found in 45.7% of the black patients compared to 14.3% of the black controls (corrected P value < 0.035) and DRw4 was found in 71.4% of the white patients compared to 40.0% of the white controls (corrected P value < 0.035). These data indicate that immunogenetic factors related to DRw4 are important in the development of rheumatoid arthritis in American blacks as well as whites.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0004-3591
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
23
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1241-5
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:6934774-Adult,
pubmed-meshheading:6934774-African Continental Ancestry Group,
pubmed-meshheading:6934774-Aged,
pubmed-meshheading:6934774-Arthritis, Rheumatoid,
pubmed-meshheading:6934774-Gold,
pubmed-meshheading:6934774-HLA Antigens,
pubmed-meshheading:6934774-Histocompatibility Antigens Class II,
pubmed-meshheading:6934774-Humans,
pubmed-meshheading:6934774-Middle Aged,
pubmed-meshheading:6934774-Penicillamine,
pubmed-meshheading:6934774-Rheumatoid Factor,
pubmed-meshheading:6934774-United States
|
pubmed:year |
1980
|
pubmed:articleTitle |
Association of HLA-DRw4 with rheumatoid arthritis in black and white patients.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|