Linked Life Data

6931485

Source:http://linkedlifedata.com/resource/pubmed/id/6931485

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1980-10-27
pubmed:abstractText
Orthodontists usually assume that genetic factors are of major significance to the development of malocclusion. Studies of twin similarities have lent support to this concept. Use of the twin model to estimate genetic variance, however, involves the assumptions that there are no mean or total variance inequalities between monozygotic and dizygotic twins. The environmental (including biologic) differences between monozygotic and dizygotic twin development may therefore constitute a source of bias. Genetic variance and heritability were estimated for a series of arch and occlusal traits in sixty twins using recently developed methods that are unbiased by variance heterogeneity between zygosities. Heterogeneity was demonstrated for twenty of the forty traits, suggesting considerable amounts of hidden environmental determinance. Tooth-displacement means differed between monozygotes and dizygotes, indicating bias in that trait's genetic variance analysis. Significant heritability could not be demonstrated for overbite, overjet, buccal segment relation, total tooth displacement, and occlusal discrepancies in arch shape. Arch size, individual tooth displacement scores, and cross-bite show significant genetic variance, averaging only about 36 percent of the total variance of these traits.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0002-9416
pubmed:author
pubmed:issnType
Print
pubmed:volume
78
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
140-54
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Genetic analysis of occlusal variation in twins.
pubmed:publicationType
Journal Article, Comparative Study