Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1980-9-28
pubmed:abstractText
It is impossible to prove that any chemical, natural or man-made, cannot cause cancer in man. However, it is possible to estimate the relative degrees of risk associated with various agents. The precision of these estimations increases as experimental procedures elucidate the basic type of mechanism associated with carcinogenesis, the role of absorption, metabolism and distribution, and excretion in increasing or decreasing activity, and the dose dependency of metabolic pathways. We must constantly strive to make the most accurate risk estimations possible so that the complex issues of risk/benefit may be properly considered.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0171-9750
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
79-94
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Non-linear pharmacokinetic parameters need to be considered in high dose/low dose extrapolation.
pubmed:publicationType
Journal Article