Linked Life Data

6929651

Source:http://linkedlifedata.com/resource/pubmed/id/6929651

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1980-7-26
pubmed:abstractText
A case of null cell acute lymphoblastic leukemia (ALL) terminating in malignant histiocytosis (HMR) is discussed. The patient was a 22-year-old man who presented in January 1976 with ALL. Cell surface markers on the bone-marrow blasts showed that 1% formed rosettes with sheep erythrocytes (T cells) and 4% showed immunofluorescent staining for immunoglobulin; terminal transferase levels were elevated, confirming the diagnosis of null cell ALL. The patient was treated intensively with a combination of chemotherapy and cranial irradiation. One year after diagnosis, he was maintained in partial relapse (10-15% blasts). His terminal episode was characterized by pancytopenia. The bone marrow was replaced by malignant histiocytes. Cell surface membrane staining for cytophilic antibody was positive, whereas terminal transferase levels were in the range of nonlymphoid malignancies.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0002-9173
pubmed:author
pubmed:issnType
Print
pubmed:volume
73
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
725-30
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Null cell (non-T, non-B) acute lymphoblastic leukemia terminating as malignant histiocytosis.
pubmed:publicationType
Journal Article, Case Reports