Linked Life Data

6928046

Source:http://linkedlifedata.com/resource/pubmed/id/6928046

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1980-3-17
pubmed:abstractText
Plasminogen-activating activity (PAA) was determined on cytosols prepared from human breast cancers. Coincident assays of steroid-binding proteins were obtained for 119 patients. Significant positive correlations were found between PAA and binding of: 1) estrogen (P less than 0.01), 2) progestin (P less than 0.001), and 3) triamcinolone (P = 0.01). Stepwise regression analysis indicated that variations in the levels of progestin binding accounted for 17% (P less than 0.01) and variations in the levels of triamcinolone binding for 3% (P = 0.05) of the variation observed in PAA. Use of the median value of each assay to discriminate positive from negative values accentuated the positive correlation between PAA and binding of 1) estrogen (P = 3.9 X 10(-5), 2) progestin (P = 1.9 X 10(-4), and 3) triamcinolone (P = 6.1 X 10(-5). Preliminary results suggested that values of PAA equal to or greater than the median correlated positively with response to treatment by hormone manipulation (P = 0.0549). Possible significance of these observations was discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0027-8874
pubmed:author
pubmed:issnType
Print
pubmed:volume
64
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Plasminogen-activating activity: association with steroid binding by cytosols of human breast cancers.
pubmed:publicationType
Journal Article, Comparative Study