Linked Life Data

6911031

Source:http://linkedlifedata.com/resource/pubmed/id/6911031

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1981-10-25
pubmed:abstractText
This paper presents a review of literature on the chemical composition of khat (Catha edulis Forsk., Celastraceae). The effect of chewing fresh khat could not be explained satisfactorily by the action of d-norpseudoephedrine which was, for a long time, believed to be the only stimulant in khat. A comprehensive study on the chemical composition of khat was undertaken at the United Nations narcotics Laboratory with the aim of isolating and characterizing the principles of the fresh plant active on the central nervous system. This work resulted in the detection and isolation of cathinone, a phenylalkylamine characterized as (-)-alpha-aminopropiophenone. It is the main phenylalkylamine component of fresh khat, and pharmacological studies indicate that it may be the compound responsible for the characteristic stimulant activity and abuse potential of the plant. Some of its "decomposition" or transformation products, such as norpseudoephedrine, norephedrine, 3,6-dimethyl-2,5-diphenylpyrazine, and 1-phenyl-1,2-propanedione, have also been isolated and characterized.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0007-523X
pubmed:author
pubmed:issnType
Print
pubmed:volume
32
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5-35
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
The chemistry of khat.
pubmed:publicationType
Journal Article