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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1981-5-21
|
| pubmed:abstractText |
A serine protease active on insoluble elastin at neutral pH has been isolated from human aortic media employing a Lima-bean trypsin inhibitor - Sepharose column. It is also hydrolyzed Suc (Ala)3 pna and casein but was found inactive against Benzoyl-Tyr-pna and Benzoyl-Arg-pna. Its apparent molecular weight as determined by SDS-PAGE was 22,300 Daltons. It differs from other elastases of human origin (human pancreatic elastase-1, human pancreatic elastase-2, human leucocyte elastase) on the basis of amino-acid composition and immunological specificity.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0098-6127
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
7
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
290-302
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:6908522-Amino Acids,
pubmed-meshheading:6908522-Aorta,
pubmed-meshheading:6908522-Chromatography, Affinity,
pubmed-meshheading:6908522-Elastin,
pubmed-meshheading:6908522-Humans,
pubmed-meshheading:6908522-Hydrogen-Ion Concentration,
pubmed-meshheading:6908522-Pancreatic Elastase,
pubmed-meshheading:6908522-Substrate Specificity
|
| pubmed:year |
1980
|
| pubmed:articleTitle |
Isolation and partial characterization of an elastase-type enzyme from human arterial wall by lima-bean trypsin inhibitor affinity chromatography.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|