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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1981-1-29
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pubmed:abstractText |
In March 1978, a strain of methicillin-resistant Staphylococcus aureus was introduced from the community into a university hospital. Within 6 months of admission of the index case, methicillin-resistant S. aureus was isolated from 30 additional patients, 22 of whom were epidemiologically linked by a common phage type (6/47/54/75/83A) and roommate-to-roommate spread. Sixteen of 31 cases were infected, six with bacteremia. Patients with infections received cephalosporins more frequently before infection than did control subjects (p < 0.05). Patients acquiring methicillin-resistant S. aureus in the intensive care unit had a longer mean stay, had higher overall mortality, and received nafcillin and aminoglycosides more frequently than did cohorted control subjects. By mid-1979, methicillin-resistant S. aureus accounted for 38%, 31%, and 24% of all nosocomial S. aureus postoperative wound, pulmonary, and bloodstream infections, respectively. In hospitals with significant methicillin-resistant S. aureus isolation rates, initial empiric therapy of presumed S. aureus infection with vancomycin seems warranted.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0003-4819
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
93
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
526-32
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6904159-Adult,
pubmed-meshheading:6904159-Cross Infection,
pubmed-meshheading:6904159-Disease Outbreaks,
pubmed-meshheading:6904159-Female,
pubmed-meshheading:6904159-Humans,
pubmed-meshheading:6904159-Intensive Care Units,
pubmed-meshheading:6904159-Male,
pubmed-meshheading:6904159-Methicillin,
pubmed-meshheading:6904159-Microbial Sensitivity Tests,
pubmed-meshheading:6904159-Middle Aged,
pubmed-meshheading:6904159-Penicillin Resistance,
pubmed-meshheading:6904159-Staphylococcal Infections,
pubmed-meshheading:6904159-Staphylococcus aureus,
pubmed-meshheading:6904159-Virginia
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pubmed:year |
1980
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pubmed:articleTitle |
Methicillin-resistant Staphylococcus aureus: introduction and spread within a hospital.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|