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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1980-12-18
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pubmed:abstractText |
Urinary kallikrein excretion was studied in young, stroke-prone, spontaneously hypertensive rats (spSHR). Seven-week-old spSHR were found to excrete more kallikrein into the urine than normotensive Wistar Kyoto control rats (WKR). "Chemical sympathectomy", induced by 6-hydroxydopamine (6-OHDA) immediately after birth, resulted in normotensive blood-pressure levels and in a reduction of kallikrein in spSHR. In normotensive WKR, blood pressure and urinary kallikrein excretion were only slightly diminished by 6-OHDA. The results suggest a relationship between sympathetic activity and kallikrein excretion, being especially pronounced in spSHR, which have an elevated sympathetic activity.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0028-1298
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
313
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
155-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6903261-Animals,
pubmed-meshheading:6903261-Animals, Newborn,
pubmed-meshheading:6903261-Blood Pressure,
pubmed-meshheading:6903261-Hydroxydopamines,
pubmed-meshheading:6903261-Hypertension,
pubmed-meshheading:6903261-Kallikreins,
pubmed-meshheading:6903261-Male,
pubmed-meshheading:6903261-Rats
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pubmed:year |
1980
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pubmed:articleTitle |
Increased kallikrein excretion in spontaneously hypertensive rats and its inhibition by 6-hydroxydopamine.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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