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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
17
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pubmed:dateCreated |
1982-12-21
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pubmed:abstractText |
Quasi-elastic and 90 degrees light scattering were used to study the aggregation of dipalmitoylphosphatidylcholine vesicles at temperatures below the gel-liquid-crystalline phase transition as a function of concentration, temperature, and size. Increased vesicle concentration did not appreciably change aggregate size but did change the total number of aggregates in a manner consistent with a bimolecular collisional mechanism for the conversion of aggregates to fused vesicles. Increased temperature decreased aggregation, indicating that the disaggregation rate constant increased faster than the aggregation rate constant. As a function of size, aggregation decreased slightly from small to 700 A diameter vesicles and increased considerably for 950 A diameter vesicles. A model of the interaction of small vesicles below the gel-liquid-crystalline phase transition is presented in which aggregation precedes fusion and collision between aggregates triggers fusion.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0006-2960
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
17
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4133-9
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:6896999-Chemistry, Physical,
pubmed-meshheading:6896999-Cold Temperature,
pubmed-meshheading:6896999-Kinetics,
pubmed-meshheading:6896999-Light,
pubmed-meshheading:6896999-Liposomes,
pubmed-meshheading:6896999-Physicochemical Phenomena,
pubmed-meshheading:6896999-Pulmonary Surfactants,
pubmed-meshheading:6896999-Scattering, Radiation
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pubmed:year |
1982
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pubmed:articleTitle |
Aggregation of dipalmitoylphosphatidylcholine vesicles.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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