pubmed-article:6891244 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:6891244 | lifeskim:mentions | umls-concept:C1522564 | lld:lifeskim |
pubmed-article:6891244 | lifeskim:mentions | umls-concept:C0008593 | lld:lifeskim |
pubmed-article:6891244 | lifeskim:mentions | umls-concept:C0042890 | lld:lifeskim |
pubmed-article:6891244 | lifeskim:mentions | umls-concept:C0221198 | lld:lifeskim |
pubmed-article:6891244 | lifeskim:mentions | umls-concept:C1545588 | lld:lifeskim |
pubmed-article:6891244 | pubmed:issue | 11 | lld:pubmed |
pubmed-article:6891244 | pubmed:dateCreated | 1983-2-25 | lld:pubmed |
pubmed-article:6891244 | pubmed:abstractText | Effects of high doses of vitamin D on rat hearts were investigated 72 h after the administration of 500 000 U/kg. Histological examination showed disseminated focal necrosis with reactive round cell and granulocytic infiltration in the heart. The calcium content was increased by about 70%. These findings indicate vitamin D-induced myocardial lesions. Heart mitochondrial calcium binding and uptake activities were lower than in control animals. Na+-K+-ATPase activity of heart washed particles was reduced by the treatment with vitamin D whereas neither calcium binding and uptake activities of cardiac sarcoplasmic reticulum nor myofibrillar ATPase activity were affected. Carbocromen (20 and 100 mg/kg/d) treatment reduced vitamin D-induced decreases in mitochondrial calcium accumulating ability and Na+-K+-ATPase activity of heart washed particle, suggesting a beneficial effect of carbocromen against vitamin D-induced cardiac injury. | lld:pubmed |
pubmed-article:6891244 | pubmed:language | eng | lld:pubmed |
pubmed-article:6891244 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6891244 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:6891244 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6891244 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6891244 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6891244 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:6891244 | pubmed:issn | 0004-4172 | lld:pubmed |
pubmed-article:6891244 | pubmed:author | pubmed-author:TakeiYY | lld:pubmed |
pubmed-article:6891244 | pubmed:author | pubmed-author:KeilMM | lld:pubmed |
pubmed-article:6891244 | pubmed:author | pubmed-author:SchravenEE | lld:pubmed |
pubmed-article:6891244 | pubmed:author | pubmed-author:NitzR ERE | lld:pubmed |
pubmed-article:6891244 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:6891244 | pubmed:volume | 32 | lld:pubmed |
pubmed-article:6891244 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:6891244 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:6891244 | pubmed:pagination | 1412-7 | lld:pubmed |
pubmed-article:6891244 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
pubmed-article:6891244 | pubmed:meshHeading | pubmed-meshheading:6891244-... | lld:pubmed |
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pubmed-article:6891244 | pubmed:year | 1982 | lld:pubmed |
pubmed-article:6891244 | pubmed:articleTitle | Vitamin D-induced myocardial lesions and the protection by carbocromen. | lld:pubmed |
pubmed-article:6891244 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:6891244 | pubmed:publicationType | In Vitro | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:6891244 | lld:pubmed |