Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
22
|
pubmed:dateCreated |
1983-2-25
|
pubmed:abstractText |
The influence of anti-inflammatory methane sulfonanilides on the arachidonic acid metabolism in ram seminal vesicle homogenate depends on the pK3 of the individual substance: more acidic compounds suppress, less acidic compounds stimulate PG synthesis and enhance the PGH2/PGG2 ratio. As oxygen radicals are liberated during the conversion of PGG2 to PGH2 it is suggested that the less acidic methane sulfonanilides are scavengers of the (pro-inflammatory) oxygen radicals.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0006-2952
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
31
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
3591-6
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:6891217-Animals,
pubmed-meshheading:6891217-Anti-Inflammatory Agents,
pubmed-meshheading:6891217-Humans,
pubmed-meshheading:6891217-Kinetics,
pubmed-meshheading:6891217-Male,
pubmed-meshheading:6891217-Prostaglandin Antagonists,
pubmed-meshheading:6891217-Prostaglandins,
pubmed-meshheading:6891217-Seminal Vesicles,
pubmed-meshheading:6891217-Sheep,
pubmed-meshheading:6891217-Sulfonamides
|
pubmed:year |
1982
|
pubmed:articleTitle |
Non-steroidal anti-inflammatories--XII. Mode of action of anti-inflammatory methane sulfonanilides.
|
pubmed:publicationType |
Journal Article
|