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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
|
pubmed:dateCreated |
1982-12-18
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pubmed:abstractText |
Isovolumetric pressure-volume relations, parameters of contractility and the resting tension curve were recorded in Wistar rats prior and during acute intoxication with ethylalcohol. Parameters were recorded at blood levels between 6.0% and 2.0% of the intravenously infused alcohol. At the high blood alcohol level, maximal isovolumetric pressure is diminished by 24%, maximal rate of pressure rise by 42%, as compared with controls, whereas enddiastolic pressure increased by 32% and enddiastolic volume by 11%. Significant impairment of hemodynamics is also present at a blood alcohol level of 2.0%. These findings point to a dose-dependent cardiodepression in acute alcohol intoxication.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0300-5860
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
71
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
533-8
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:6890277-Alcoholic Intoxication,
pubmed-meshheading:6890277-Animals,
pubmed-meshheading:6890277-Blood Pressure,
pubmed-meshheading:6890277-Blood Volume,
pubmed-meshheading:6890277-Depression, Chemical,
pubmed-meshheading:6890277-Dose-Response Relationship, Drug,
pubmed-meshheading:6890277-Electrocardiography,
pubmed-meshheading:6890277-Ethanol,
pubmed-meshheading:6890277-Hemodynamics,
pubmed-meshheading:6890277-Humans,
pubmed-meshheading:6890277-Male,
pubmed-meshheading:6890277-Rats,
pubmed-meshheading:6890277-Rats, Inbred Strains
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pubmed:year |
1982
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pubmed:articleTitle |
[Dose-dependent cardiodepression in acute alcohol intoxication in the rat].
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pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
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