Switch to
Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
|
pubmed:dateCreated |
1982-12-3
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pubmed:abstractText |
Swelling of the optic disc and loss of tendon reflexes developed in a 3 1/2-year-old girl after 11 high-dose courses of cisplatin (cis-dichlorodiammine platinum [II]) therapy for recurrent sacrococcygeal teratoma. Postmortem examination demonstrated optic disc swelling; the spinal cord showed loss of myelinated fibers and gliosis of the dorsal columns. To our knowledge this case is the first in which the neuropathologic changes associated with cisplatin therapy have been demonstrated by postmortem examination.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0003-9942
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
719-20
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6889850-Child, Preschool,
pubmed-meshheading:6889850-Cisplatin,
pubmed-meshheading:6889850-Female,
pubmed-meshheading:6889850-Humans,
pubmed-meshheading:6889850-Optic Nerve Diseases,
pubmed-meshheading:6889850-Spinal Cord Diseases,
pubmed-meshheading:6889850-Spinal Neoplasms,
pubmed-meshheading:6889850-Teratoma
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pubmed:year |
1982
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pubmed:articleTitle |
Neurotoxic effects of cisplatin therapy.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Case Reports
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