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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1982-12-2
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pubmed:abstractText |
The hypothalamohypophyseal and renin-angiotensin systems of rats were studied in health, during long-term alcoholization and formation of artificial alcohol motivation. It was disclosed that a single intracerebral administration of angiotensin-II had a long-term (for 1--2 weeks) inhibitory effect on alcohol consumption in rats. At the same time a decrease in the activity of the vasopressin-synthesizing neurosecretory cells of the hypothalamic supraoptic nucleus and Hering's bodies as well as compensatory activation of the peripheral parts of the renin-angiotensin system were demonstrated. Apparently, the inclusion of ethanol metabolites in the normal brain metabolism appreciably changes the role of angiotensin-II in hypothalamohypophyseal and renin-angiotensin system functions.
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pubmed:language |
rus
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0365-9615
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
93
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
68-71
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pubmed:dateRevised |
2008-10-8
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pubmed:meshHeading |
pubmed-meshheading:6889448-Alcohol Drinking,
pubmed-meshheading:6889448-Alcoholism,
pubmed-meshheading:6889448-Angiotensin II,
pubmed-meshheading:6889448-Animals,
pubmed-meshheading:6889448-Drinking,
pubmed-meshheading:6889448-Humans,
pubmed-meshheading:6889448-Hypothalamo-Hypophyseal System,
pubmed-meshheading:6889448-Male,
pubmed-meshheading:6889448-Rats,
pubmed-meshheading:6889448-Rats, Inbred Strains,
pubmed-meshheading:6889448-Renin-Angiotensin System,
pubmed-meshheading:6889448-Time Factors
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pubmed:year |
1982
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pubmed:articleTitle |
[Role of angiotensin II in the mechanisms of ethanol consumption regulation in rats].
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pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
|