Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1982-12-2
pubmed:abstractText
The hypothalamohypophyseal and renin-angiotensin systems of rats were studied in health, during long-term alcoholization and formation of artificial alcohol motivation. It was disclosed that a single intracerebral administration of angiotensin-II had a long-term (for 1--2 weeks) inhibitory effect on alcohol consumption in rats. At the same time a decrease in the activity of the vasopressin-synthesizing neurosecretory cells of the hypothalamic supraoptic nucleus and Hering's bodies as well as compensatory activation of the peripheral parts of the renin-angiotensin system were demonstrated. Apparently, the inclusion of ethanol metabolites in the normal brain metabolism appreciably changes the role of angiotensin-II in hypothalamohypophyseal and renin-angiotensin system functions.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0365-9615
pubmed:author
pubmed:issnType
Print
pubmed:volume
93
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
68-71
pubmed:dateRevised
2008-10-8
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
[Role of angiotensin II in the mechanisms of ethanol consumption regulation in rats].
pubmed:publicationType
Journal Article, Comparative Study, English Abstract