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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1983-10-28
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pubmed:abstractText |
Serum calcium and magnesium levels were studied during neuroleptic treatment in a group of 29 chronic schizophrenic inpatients who had previously remained drug free for at least 4 weeks. The drug-free values of both electrolytes were not significantly different between patients and controls. In three patients who developed catatonic stupor during the drug-free period, calcium was significantly increased at the onset of the catatonic manifestations. Both electrolytes were significantly decreased in the whole group during treatment; the magnitude of the decrease was independent of the neuroleptic used. No correlation was found between the observed increase in prolactin and calcium changes. Patients who remained free of extra-pyramidal symptoms had a higher mean drug-free magnesium to calcium ratio compared to those who developed such symptoms. Our study provides evidence for an interconnection between serum electrolyte changes and neuroleptic drug action.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Calcium,
http://linkedlifedata.com/resource/pubmed/chemical/Fluphenazine,
http://linkedlifedata.com/resource/pubmed/chemical/Loxapine,
http://linkedlifedata.com/resource/pubmed/chemical/Magnesium,
http://linkedlifedata.com/resource/pubmed/chemical/Pimozide
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0271-0749
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
3
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
212-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:6886033-Calcium,
pubmed-meshheading:6886033-Chronic Disease,
pubmed-meshheading:6886033-Dyskinesia, Drug-Induced,
pubmed-meshheading:6886033-Female,
pubmed-meshheading:6886033-Fluphenazine,
pubmed-meshheading:6886033-Humans,
pubmed-meshheading:6886033-Loxapine,
pubmed-meshheading:6886033-Magnesium,
pubmed-meshheading:6886033-Male,
pubmed-meshheading:6886033-Middle Aged,
pubmed-meshheading:6886033-Pimozide,
pubmed-meshheading:6886033-Schizophrenia
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pubmed:year |
1983
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pubmed:articleTitle |
Serum calcium and magnesium levels in chronic schizophrenics.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|